Arquivo mensal: novembro de 2012


95% Confidence Intervals

www.graphpad.com/quickcalcs/ConfInterval1.cfm Confidence interval of a proportion or count www.ruf.rice.edu/~lane/stat_sim/conf_interval/ Confidence intervals www.medicine.ox.ac.uk/bandolier/painres/download/whatis/What_are_Conf_Inter.pdf What are confidence intervals and p-values? www.stat.sc.edu/~west/javahtml/ConfidenceInterval.html Confidence Interval Applet findarticles.com/p/articles/mi_qa3950/is_200804/ai_n25501727/ Using Monte Carlo simulation to teach confidence intervals www.sportsci.org/resource/stats/conf_limits.ppt Planning, Performing, and Publishing Research with Confidence Limits www.statsoft.com/textbook/stpowan.html Power analysis davidmlane.com/hyperstat/confidence_intervals.html Overview of confidence intervals


Avaliação da Qualidade da Informação

bit.ly/journalclub  Avaliação da qualidade da informação: porque nem tudo que está escrito é verdade! http://lattes.cnpq.br/2259022333178681http://bit.ly/aldemarh Sumário O autor apresenta a definição, a importância, quem faz, quando fazer, onde fazer e como fazer a avaliação da qualidade da informação. É enfatizando a importância da sistematização e da estruturação do processo por […]


CONSORT Statement

Website of the CONSORT Group, containing the CONSORT statement, full explanation and checklist, related resources and contact details. Related guidelines and initiatives CONSORT flow diagram CONSORT checklist The CONSORT Statement The CONSORT Statement is intended to improve the reporting of a randomized controlled trial (RCT), enabling readers to understand a trial’s design, conduct, analysis […]


Clinicalevidence vs. Jamaevidence

http://www.clinicalevidence.com Clinical Evidence comprises an international database of high-quality, rigorously developed systematic overviews assessing the benefits and harms of treatments, and a suite of EBM resources and training materials. Users’ Guide Interactive Web site is a joint project between the Centre for Health Evidence and JAMA & Archives Journals. The content is based on the popular Users’ Guides […]


Noninferiority trials

Kaul S, Diamond GA. Good enough: a primer on the analysis and interpretation of noninferiority trials. Ann Intern Med. 2006 Jul 4;145(1):62-9. PubMed PMID: 16818930. (PDF Clique aqui) Piaggio G, Elbourne DR, Altman DG, Pocock SJ, Evans SJ; CONSORT Group. Reporting of noninferiority and equivalence randomized trials: an extension of […]


Estatística: lista de artigos básicos

Segue abaixo uma lista de artigos básicos de estatística. São de leitura obrigatória para quem quer ter o conhecimento mínimo sobre o tema. A primeira lista é uma série de quatro artigos publicados no Canadial Medical Association Journal e a segunta lista é uma série de dois artigos publicados no British Medical Journal. […]


International Conference on Harmonisation (ICH)

“Quality” Topics, i.e., those relating to chemical and pharmaceutical Quality Assurance (Stability Testing, Impurity Testing, etc.) “Safety” Topics, i.e., those relating to in vitro and in vivo pre-clinical studies (Carcinogenicity Testing, Genotoxicity Testing, etc.) “Efficacy” Topics, i.e., those relating to clinical studies in human subject (Dose Response Studies, Good Clinical […]


Simulação de ensaios clínicos

www.randomization.orgA free software package that can simulate Randomized Controlled Clinical Trials (RCTs). With the CTS a user can explore aspects of the design, conduction and analyses of RCTs Counsell CE, Clarke MJ, Slattery J, Sandercock PA. The miracle of DICE therapy for acute stroke: fact or fictional product of subgroup […]


The What is …? series

http://www.whatisseries.co.uk The What is …? series is intended to demystify some of the terminology, techniques and practices used to assess clinical and economic evidence within healthcare. It contains a range of titles covering: Health economics Statistics Evidence-based medicine The NHS and health technology assessment The series aims to provide healthcare professionals […]


Conflito de interesse

O conflito de interesse é um conjunto de condições nas quais o julgamento de um profissional a respeito de um interesse primário tende a ser influenciado indevidamente por um interesse secundário. De modo geral, as pessoas tendem a identificar conflito de interesses apenas como as situações que envolvem aspectos econômicos. […]