{"id":2320,"date":"2012-11-18T16:23:58","date_gmt":"2012-11-18T19:23:58","guid":{"rendered":"http:\/\/www.decisaoclinica.com\/blog\/?p=2320"},"modified":"2012-11-18T16:23:58","modified_gmt":"2012-11-18T19:23:58","slug":"noninferiority-trials","status":"publish","type":"post","link":"https:\/\/www.usinadepesquisa.com\/?p=2320","title":{"rendered":"Noninferiority trials"},"content":{"rendered":"<p><strong><img decoding=\"async\" alt=\"\" src=\"http:\/\/www.decisaoclinica.com\/images\/stories\/350px-noninferiority_and_equivalency_randomized_controlled_trials.jpg\" border=\"0\" \/><\/strong><\/p>\n<ul>\n<li>Kaul S, Diamond GA. Good enough: a primer on the analysis and interpretation of noninferiority trials. Ann Intern Med. 2006 Jul 4;145(1):62-9. PubMed PMID: 16818930. (<a href=\"http:\/\/www.annals.org\/content\/145\/1\/62.full.pdf+html\">PDF Clique aqui<\/a>)<\/li>\n<li>Piaggio G, Elbourne DR, Altman DG, Pocock SJ, Evans SJ; CONSORT Group. Reporting of noninferiority and equivalence randomized trials: an extension of the CONSORT statement. JAMA. 2006 Mar 8;295(10):1152-60. Erratum in: JAMA. 2006 Oct 18;296(15):1842. PubMed PMID: 16522836. (<a href=\"http:\/\/jama.ama-assn.org\/cgi\/reprint\/295\/10\/1152.pdf\">PDF clique aqui<\/a>)<\/li>\n<li>Food and Drug Administration, HHS. International Conference on Harmonisation; choice of control group and related issues in clinical trials; availability. Notice. Fed Regist. 2001 May 14;66(93):24390-1. PubMed PMID: 12356096. Dispon\u00edvel em:<a href=\"http:\/\/www.ich.org\/MediaServer.jser?@_ID=486&amp;@_MODE=GLB\">www.ich.org\/MediaServer.jser?@_ID=486&amp;@_MODE=GLB<\/a><\/li>\n<li><a href=\"http:\/\/www.graphpad.com\/library\/BiostatsSpecial\/article_182.htm\">www.graphpad.com\/library\/BiostatsSpecial\/article_182.htm<\/a><br \/>\nTesting for equivalence is not just the opposite of testing for significant differences<\/li>\n<\/ul>\n<p><strong><img decoding=\"async\" alt=\"\" src=\"http:\/\/www.decisaoclinica.com\/images\/stories\/equivalence.png\" border=\"0\" \/><br \/>\n<\/strong><\/p>\n<p>&nbsp;<\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<p><strong>Recursos adicionais<\/strong><\/p>\n<ul>\n<li><a href=\"http:\/\/www.rds-sc.org\/planning-a-study\/study-design\/quantitative-studies\/clinical-trials\/non-inferiority-trials\/\">www.rds-sc.org\/planning-a-study\/study-design\/quantitative-studies\/clinical-trials\/non-inferiority-trials\/<\/a><\/li>\n<li><a href=\"http:\/\/www.cct.cuhk.edu.hk\/stat\/proportion\/OSp_sup.htm\">www.cct.cuhk.edu.hk\/stat\/proportion\/OSp_sup.htm<\/a><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Kaul S, Diamond GA. Good enough: a primer on the analysis and interpretation of noninferiority trials. Ann Intern Med. 2006 Jul 4;145(1):62-9. PubMed PMID: 16818930. (PDF Clique aqui) Piaggio G, Elbourne DR, Altman DG, Pocock SJ, Evans SJ; CONSORT Group. Reporting of noninferiority and equivalence randomized trials: an extension of the CONSORT statement. JAMA. 2006 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3176,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,1],"tags":[],"class_list":{"0":"post-2320","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-geral","8":"category-uncategorized","9":"czr-hentry"},"_links":{"self":[{"href":"https:\/\/www.usinadepesquisa.com\/index.php?rest_route=\/wp\/v2\/posts\/2320","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.usinadepesquisa.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.usinadepesquisa.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.usinadepesquisa.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.usinadepesquisa.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2320"}],"version-history":[{"count":0,"href":"https:\/\/www.usinadepesquisa.com\/index.php?rest_route=\/wp\/v2\/posts\/2320\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.usinadepesquisa.com\/index.php?rest_route=\/"}],"wp:attachment":[{"href":"https:\/\/www.usinadepesquisa.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2320"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.usinadepesquisa.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2320"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.usinadepesquisa.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2320"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}